A new study is presenting the first published data from preliminary human trials investigating the effect of psilocybin-assisted psychotherapy to treat major depressive disorder (MDD). The incredibly positive results have been described as just a “taste of things to come” with larger a Phase 2 trial well underway.

The US Food and Drug Administration (FDA) has granted psilocybin, the primary psychoactive compound in magic mushrooms, a Breakthrough Therapy designation on two occasions over the past 24 months. Initially the designation was granted to help accelerate trials for severe treatment-resistant depression, but more recently the classification focused on trials for major depressive disorder.

Philanthropist Tim Ferriss, who financially supported this preliminary study, calls this new research a “critically important proof of concept.” A well-known advocate for psychedelic medicine, Ferriss says these promising results are only the beginning of a major paradigm shift in mental health treatment.

“How do we explain the incredible magnitude and durability of effects?” asks Ferriss. “Treatment research with moderate to high doses of psychedelics may uncover entirely new paradigms for understanding and improving mood and mind. This is a taste of things to come from Johns Hopkins.”

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Psilocybin therapy 4 times more effective than antidepressants, study finds

A new study is presenting the first published data from preliminary human trials investigating the effect of psilocybin-assisted psychotherapy to treat major depressive disorder (MDD). The incredibly positive results have been described as just a “taste of things to come” with larger a Phase 2…..


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