From the prestigious Salk Institute…. …although just a human tissue study, some genuinely promising news on medical cannabis’ potential in the treatment of the amyloid plaques found in Alzheimer’s disease.

“An active compound in marijuana called tetrahydrocannabinol (THC) has been found to promote the removal of toxic clumps of amyloid beta protein in the brain, which are thought to kickstart the progression of Alzheimer’s disease.

The finding supports the results of previous studies that found evidence of the protective effects of cannabinoids, including THC, on patients with neurodegenerative disease.

‘Although other studies have offered evidence that cannabinoids might be neuroprotective against the symptoms of Alzheimer’s, we believe our study is the first to demonstrate that cannabinoids affect both inflammation and amyloid beta accumulation in nerve cells,’ says one of the team, David Schubert from the Salk Institute for Biological Studies in California.

Schubert and his colleagues tested the effects of THC on human neurons grown in the lab that mimic the effects of Alzheimer’s disease.

Over the years, research has suggested that by binding to [the receptors in the human endocannabinoid system], THC could be having another effect on aging brains, because it appears to helps the body clear out the toxic accumulations – or ‘plaques’ – of amyloid beta.

No one’s entirely sure what causes Alzheimer’s disease, but it’s thought to result from a build-up of two types of lesions: amyloid plaques and neurofibrillary tangles.

Amyloid plaques sit between the neurons as dense clusters of beta-amyloid molecules – a sticky type of protein that easily clumps together – and neurofibrillary tangles are caused by defective tau proteins that clump up into a thick, insoluble mass in the neurons.

It’s not clear why these lesions begin to appear in the brain, but studies have linked inflammation in the brain tissue to the proliferation of plaques and neurofibrillary tangles. So if we can find something that eases brain inflammation while at the same time encourages the body to clear out these lesions, we could be on the way to finding the first effective treatment for Alzheimer’s ever.”

Much more in the article… …and again, this is early stage work, but in any event don’t be fooled by opponents: properly conducted scientific research doesn’t have to be specifically blessed by the anti-cannabis, pro-synthetic medicines FDA bureaucrats to keep adding to the growing number of known benefits of medicinal cannabis.

#MMJ #UTpol #Research #Alzheimers #TRUCE    

See full article – Marijuana Compound Removes Toxic Alzheimer’s Protein From The Brain