Mined from the ground vs. grown in it: Marinol vs. THC – an extensive intro.


…Dronabinol is a synthetic [drug] that goes by the trade name Marinol. It is a cannabis pharmaceutical that was created in a laboratory….

In the U.S., the FDA-approved Marinol now helps with the treatment of, “anorexia associated with weight loss in patients with AIDS,” and “nausea and vomiting associated with cancer chemotherapy in patients who have failed to respond adequately to conventional antiemetic treatments.”

This drug comes in three different doses (2.5 mg, 5 mg, and 10 mg) and starts at roughly eleven dollars per 2.5 mg dose. Calculated off the recommended twice-daily dosing schedule, that’s over $8,000 for an annual prescription [of the MINIMUM dose]. Is that affordable healthcare? Advocates would argue that cannabis is much cheaper, especially in states that allow home grow [explained further in the article].

But, how does the ‘real thing’ compare to cannabis pharmaceuticals?

What is the Difference Between THC and Marinol?

Chemical Composition: Marinol contains a long list of ingredients, most of which are synthetics: FD&C Blue No. 1 (5 mg), FD&C Red No. 40 (5 mg), FD&C Yellow No. 6 (5 mg and 10 mg), gelatin, glycerin, methylparaben, propylparaben, sesame oil, and titanium dioxide.

Cannabis has a much more organic profile and if THC isolate is the medicine of choice (against Marinol, a synthetic THC isolate) that is a single ingredient: THC.

Medical cannabis, in flower form, contains hundreds of natural compounds (cannabinoids, terpenes, flavonoids, and the like). Research from 2017 suggests that each individual component has therapeutic potential.

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Much more in the article. If there's anything superior about the FDA-approved product though – from the patient satisfaction and clinical effectiveness points of view at least – it absolutely escapes us.

Give us real medical cannabis please!


How does Marinol Compare to THC?

All cannabinoids are not created equal, especially when it comes to cannabis pharmaceuticals. How do these compare to the plant for efficacy and cost?